Lead Investigator, Clinical Development/Operations at PostEra


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PostEra is Hiring

Job Info:
  • Company PostEra
  • Position Lead Investigator, Clinical Development/Operations
  • Location Remote.
  • Source Lever
  • Published June 23, 2025(45+ days ago)
  • Category Operations
  • Type Full-Time
  • Experience Lead


Job Description

PostEra is building a modern, 21st-century biopharma. We use Proton, our AI platform for medicinal chemistry, to accelerate the discovery of new medicines for patients. PostEra is advancing an internal pipeline focused on Women鈥檚 Health and Reproductive Medicine while also advancing small-molecule programs through partnerships with biopharma. We've closed over $1Bn in AI partnerships, including four multi-year agreements with Pfizer and Amgen.

We鈥檝e also been an active participant in open-science projects, leading a $68M antiviral drug discovery center for pandemic preparedness, which followed on from the success of COVID Moonshot, the world鈥檚 largest open-science initiative to develop a COVID antiviral.

PostEra's Organizational Structure:
We believe time spent navigating complex hierarchies in organizations is better invested in the pursuit of novel technology and scientific discoveries. As such, our organizational structure is intentionally minimalist.
We promote a culture where individual achievement is celebrated through proportional compensation and internal recognition, including meaningful promotions.
Ultimately, our collective focus is delivering cures to patients, which we believe needs a huge amount of cross-disciplinary collaboration, so we've fitted our organizational structure to serve that end.

What would you do

  • Lead end-to-end planning and operational execution of PostEra鈥檚 early-phase clinical trials.
  • Collaborate with internal and external teams across Regulatory, CMC, Preclinical, and Translational Medicine to ensure trial readiness.
  • Manage timelines, budgets, trial site selection, and study activities.
  • Oversee CROs, vendors, and consultants to ensure high-quality trial conduct.
  • Serve as the operational point person across clinical development activities.
  • Translate the scientific strategy into executable trial designs and operational plans.

  • Experience and skills you should have

  • 15+ years of experience in Clinical Operations/Clinical Development.
  • Demonstrated ability to manage complex timelines, trial designs, and regulatory documentation.
  • Strong CRO oversight capabilities.

  • Bonus Experience and Skills

  • Experience in reproductive medicine and women鈥檚 health
  • Experience in working in a fast-paced biotech setting
  • Salary: 200k - 240k
    Equity: 0.1% - 0.2%
    Visa Sponsorship: Not at this time
    Hiring Manager: Alpha Lee

    Visit us at postera.ai

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